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1

Lymphatic filariasis and onchocerciasis

Mark J Taylor, Achim Hoerauf, Moses Bockarie

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2010

2

A survival tree method for the analysis of discrete event times in clinical and epidemiological studies

Schmid, Matthias, Küchenhoff, Helmut, Hoerauf, Achim, Tutz, Gerhard

Journal:

Statistics in Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2016

3

Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment

Ritter, Manuel, Osei-Mensah, Jubin, Debrah, Linda Batsa, Kwarteng, Alexander, Mubarik, Yusif, Debrah, Alexander Y., Pfarr, Kenneth, Hoerauf, Achim, Layland, Laura E., Mitre, Edward

Journal:

PLoS Neglected Tropical Diseases

Année:

2019

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2019

4

Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms

Achim Hoerauf, Sabine Mand, Lars Volkmann, Marcelle Büttner, Yeboah Marfo-Debrekyei, Mark Taylor, Ohene Adjei, Dietrich W Büttner

Journal:

Microbes and Infection

Année:

2003

Langue:

english

Fichier:

PDF, 756 KB

english, 2003

5

Animated documentation of the filaria dance sign (FDS) in bancroftian filariasis

Sabine Mand, Yeboah Marfo-Debrekyei, Matthias Dittrich, Kerstin Fischer, Ohene Adjei, Achim Hoerauf

Journal:

Filaria Journal

Année:

2003

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2003

6

Depletion of wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment

Achim Hoerauf, Sabine Mand, Ohene Adjei, Bernhard Fleischer, Dietrich W Büttner

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 387 KB

english, 2001

7

Neutrophil extracellular trap formation in supragingival biofilms

Hirschfeld, Josefine, Dommisch, Henrik, Skora, Philipp, Horvath, Gabor, Latz, Eicke, Hoerauf, Achim, Waller, Tobias, Kawai, Toshihisa, Jepsen, Søren, Deschner, James, Bekeredjian-Ding, Isabelle

Journal:

International Journal of Medical Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2015

8

Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis

Journal:

Current Opinion in Infectious Diseases

Année:

2008

Langue:

english

Fichier:

PDF, 339 KB

english, 2008

9

Effective inhibition of rifampin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA-polymerase inhibitor Corallopyronin A

Shima, Kensuke, Ledig, Svea, Loeper, Nathalie, Schiefer, Andrea, Pfarr, Kenneth, Hoerauf, Achim, Graspeuntner, Simon, Rupp, Jan

Journal:

International Journal of Antimicrobial Agents

Année:

2018

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2018

10

ADLOC: An Aptamer-Displacement Assay Based on Luminescent Oxygen Channeling

Dipl.-Chem. Björn Niebel, Christian Lentz, Dipl.-Biol. Monika Pofahl, Prof. Dr. Günter Mayer, Prof. Dr. Achim Hoerauf, Dr. Kenneth M. Pfarr, Prof. Dr. Michael Famulok

Journal:

Chemistry - A European Journal

Année:

2010

Langue:

english

Fichier:

PDF, 593 KB

english, 2010

11

Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-β

Judith S. Satoguina, Tomabu Adjobimey, Kathrin Arndts, Jochen Hoch, Johannes Oldenburg, Laura E. Layland, Achim Hoerauf

Journal:

European Journal of Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 266 KB

english, 2008

12

Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties

Annette Kaiser, Ina Hammels, Andrea Gottwald, Marwa Nassar, Mai Saad Zaghloul, Basma Abdal Motaal, Joachim Hauber, Achim Hoerauf

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 410 KB

english, 2007

13

Induction of chronic colitis in IL-10 deficient mice requires IL-4

Sabine Specht, Sandra Arriens, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2006

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2006

14

Natural death of adult Onchocerca volvulus and filaricidal effects of doxycycline induce local FOXP3+/CD4+ regulatory T cells and granzyme expression

Simone Korten, Marlis Badusche, Dietrich W. Büttner, Achim Hoerauf, Norbert Brattig, Bernhard Fleischer

Journal:

Microbes and Infection

Année:

2008

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2008

15

Filaria-induced IL-10 suppresses murine cerebral malaria

Sabine Specht, Daniel Fernández Ruiz, Bettina Dubben, Susanne Deininger, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2010

Langue:

english

Fichier:

PDF, 426 KB

english, 2010

16

Transforming growth factor-beta expression by host cells is elicited locally by the filarial nematode Onchocerca volvulus in hyporeactive patients independently from Wolbachia

Simone Korten, Jussuf T. Kaifi, Dietrich W. Büttner, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2010

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2010

17

Induction of pro-inflammatory mediators in Plasmodium berghei infected BALB/c mice breaks blood-brain-barrier and leads to cerebral malaria in an IL-12 dependent manner

Kim E. Schmidt, Beatrix Schumak, Sabine Specht, Bettina Dubben, Andreas Limmer, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2011

Langue:

english

Fichier:

PDF, 747 KB

english, 2011

18

Filarial infection induces protection against P. berghei liver stages in mice

Daniel Fernández Ruiz, Bettina Dubben, Michael Saeftel, Elmar Endl, Susanne Deininger, Achim Hoerauf, Sabine Specht

Journal:

Microbes and Infection

Année:

2009

Langue:

english

Fichier:

PDF, 424 KB

english, 2009

19

Newbouldiaquinone A: A naphthoquinone–anthraquinone ether coupled pigment, as a potential antimicrobial and antimalarial agent from Newbouldia laevis

Kenneth Oben Eyong, Gabriel Ngosong Folefoc, Victor Kuete, Veronique Penlap Beng, Karsten Krohn, Hidayat Hussain, Augustin Ephram Nkengfack, Michael Saeftel, Salem Ramadan Sarite, Achim Hoerauf

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 129 KB

english, 2006

20

Neutrophil accumulation around Onchocerca worms and chemotaxis of neutrophils are dependent on Wolbachia endobacteria

Norbert W. Brattig, Dietrich W. Büttner, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2001

Langue:

english

Fichier:

PDF, 457 KB

english, 2001

21

Lack of interferon-γ confers impaired neutrophil granulocyte function and imparts prolonged survival of adult filarial worms in murine filariasis

Michael Saeftel, Lars Volkmann, Simone Korten, Norbert Brattig, Khaled Al-Qaoud, Bernhard Fleischer, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2001

Langue:

english

Fichier:

PDF, 400 KB

english, 2001

22

Monitoring of clinical and laboratory data in two cases of imported Lassa fever

Herbert Schmitz, Bernhard Köhler, Thomas Laue, Christian Drosten, Peter J Veldkamp, Stephan Günther, Petra Emmerich, Hans P Geisen, Klaus Fleischer, Matthias F.C Beersma, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2002

Langue:

english

Fichier:

PDF, 131 KB

english, 2002

23

Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis)

Judith Satoguina, Martin Mempel, John Larbi, Marlis Badusche, Cornelius Löliger, Ohene Adjei, Gabriel Gachelin, Bernhard Fleischer, Achim Hoerauf

Journal:

Microbes and Infection

Année:

2002

Langue:

english

Fichier:

PDF, 270 KB

english, 2002

24

Targeting of Wolbachia endobacteria in Litomosoides sigmodontis: comparison of tetracyclines with chloramphenicol, macrolides and ciprofloxacin

Achim Hoerauf, Lars Volkmann, Kerstin Nissen-Paehle, Christel Schmetz, Ingo Autenrieth, Dietrich W. Büttner, Bernhard Fleischer

Journal:

Tropical Medicine & International Health

Année:

2000

Langue:

english

Fichier:

PDF, 184 KB

english, 2000

25

Antibiotic therapy in murine filariasis (Litomosoides sigmodontis): comparative effects of doxycycline and rifampicin on Wolbachia and filarial viability

Lars Volkmann, Kerstin Fischer, Mark Taylor, Achim Hoerauf

Journal:

Tropical Medicine & International Health

Année:

2003

Langue:

english

Fichier:

PDF, 326 KB

english, 2003

26

Evidence againstWolbachiasymbiosis inLoa loa

Helen F McGarry, Ken Pfarr, Gill Egerton, Achim Hoerauf, Jean-Paul Akue, Peter Enyong, Samuel Wanji, Sabine L Kläger, Albert E Bianco, Nick J Beeching, Mark J Taylor

Journal:

Filaria Journal

Année:

2003

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2003

27

Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin

Alexander Yaw Debrah, Sabine Mand, Yeboah Marfo-Debrekyei, John Larbi, Ohene Adjei, Achim Hoerauf

Journal:

Filaria Journal

Année:

2006

Langue:

english

Fichier:

PDF, 537 KB

english, 2006

28

Frequent detection of worm movements in onchocercal nodules by ultrasonography

Sabine Mand, Yeboah Marfo-Debrekyei, Alex Debrah, Marcelle Buettner, Linda Batsa, Kenneth Pfarr, Ohene Adjei, Achim Hoerauf

Journal:

Filaria Journal

Année:

2005

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2005

29

Antiplasmodial activities of furoquinoline alkaloids from Teclea afzelii

Jean Duplex Wansi, Hidayat Hussain, Alain Tadjong Tcho, Simeon F. Kouam, Sabine Specht, Salem Ramadan Sarite, Achim Hoerauf, Karsten Krohn

Journal:

Phytotherapy Research

Année:

2010

Langue:

english

Fichier:

PDF, 137 KB

english, 2010

30

IL-5 is essential for vaccine-induced protection and for resolution of primary infection in murine filariasis

Coralie Martin, Khaled M. Al-Qaoud, Marie-Noëlle Ungeheuer, Kerstin Paehle, Phat N. Vuong, Odile Bain, Bernhard Fleischer, Achim Hoerauf

Journal:

Medical Microbiology and Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 241 KB

english, 2000

31

More research needed to consolidate achievements in filariasis control

Journal:

Medical Microbiology and Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 141 KB

english, 2003

32

Murine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages

Lars Volkmann, Odile Bain, Michael Saeftel, Sabine Specht, Kerstin Fischer, Frank Brombacher, Klaus I. Matthaei, Achim Hoerauf

Journal:

Medical Microbiology and Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 297 KB

english, 2003

33

Involvement of Toll-like receptor 4 in the embryogenesis of the rodent filariaLitomosoides sigmodontis

Kenneth M. Pfarr, Kerstin Fischer, Achim Hoerauf

Journal:

Medical Microbiology and Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 191 KB

english, 2003

34

Doxycycline as a novel strategy against bancroftian filariasis—depletion ofWolbachiaendosymbionts fromWuchereria bancroftiand stop of microfilaria production

Achim Hoerauf, Sabine Mand, Kerstin Fischer, Thomas Kruppa, Yeboah Marfo-Debrekyei, AlexanderYaw Debrah, KennethM. Pfarr, Ohene Adjei, DietrichW. Büttner

Journal:

Medical Microbiology and Immunology

Année:

2003

Langue:

english

Fichier:

PDF, 224 KB

english, 2003

35

Increased early local immune responses and altered worm development in high-dose infections of mice susceptible to the filariaLitomosoides sigmodontis

Simon Babayan, Tarik Attout, Sabine Specht, Achim Hoerauf, Georges Snounou, Laurent Rénia, Masataka Korenaga, Odile Bain, Coralie Martin

Journal:

Medical Microbiology and Immunology

Année:

2005

Langue:

english

Fichier:

PDF, 435 KB

english, 2005

36

Wolbachiaendobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study

Achim Hoerauf, Sabine Specht, Marcelle Büttner, Kenneth Pfarr, Sabine Mand, Rolf Fimmers, Yeboah Marfo-Debrekyei, Peter Konadu, Alexander Yaw Debrah, Claudio Bandi, Norbert Brattig, Anna Albers, John

Journal:

Medical Microbiology and Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 119 KB

english, 2008

37

Piperidones with activity againstPlasmodium falciparum

Michael Saeftel, Ramadan Salem Sarite, Tujo Njuguna, Ulrike Holzgrabe, Daniela Ulmer, Achim Hoerauf, Annette Kaiser

Journal:

Parasitology Research

Année:

2006

Langue:

english

Fichier:

PDF, 135 KB

english, 2006

38

The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria—inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase

Sabine Specht, Salem Ramadan Sarite, Ilona Hauber, Joachim Hauber, Ulf F. Görbig, Chris Meier, Dorian Bevec, Achim Hoerauf, Annette Kaiser

Journal:

Parasitology Research

Année:

2008

Langue:

english

Fichier:

PDF, 210 KB

english, 2008

39

Effects of 6-week azithromycin treatment on theWolbachiaendobacteria ofOnchocerca volvulus

Achim Hoerauf, Yeboah Marfo-Debrekyei, Marcelle Büttner, Alexander Yaw Debrah, Peter Konadu, Sabine Mand, Ohene Adjei, Dietrich W. Büttner

Journal:

Parasitology Research

Année:

2008

Langue:

english

Fichier:

PDF, 368 KB

english, 2008

40

Efficacy of 2- and 4-week rifampicin treatment on theWolbachiaofOnchocerca volvulus

Sabine Specht, Sabine Mand, Yeboah Marfo-Debrekyei, Alexander Yaw Debrah, Peter Konadu, Ohene Adjei, Dietrich W. Büttner, Achim Hoerauf

Journal:

Parasitology Research

Année:

2008

Langue:

english

Fichier:

PDF, 311 KB

english, 2008

41

Efficacy of 5-week doxycycline treatment on adultOnchocerca volvulus

Achim Hoerauf, Sabine Specht, Yeboah Marfo-Debrekyei, Marcelle Büttner, Alexander Yaw Debrah, Sabine Mand, Linda Batsa, Norbert Brattig, Peter Konadu, Claudio Bandi, Rolf Fimmers, Ohene Adjei, Dietric

Journal:

Parasitology Research

Année:

2009

Langue:

english

Fichier:

PDF, 422 KB

english, 2009

42

The nematode parasiteOnchocerca volvulusgenerates the transforming growth factor-beta (TGF-beta)

Simone Korten, Dietrich W. Büttner, Christel Schmetz, Achim Hoerauf, Sabine Mand, Norbert Brattig

Journal:

Parasitology Research

Année:

2009

Langue:

english

Fichier:

PDF, 950 KB

english, 2009

43

Newly acquiredOnchocerca volvulusfilariae after doxycycline treatment

Sabine Specht, Achim Hoerauf, Ohene Adjei, Alexander Debrah, Dietrich W. Büttner

Journal:

Parasitology Research

Année:

2009

Langue:

english

Fichier:

PDF, 438 KB

english, 2009

44

Immunohistology of ectopic secondary lymph follicles in subcutaneous nodules from patients with hyperreactive onchocerciasis (sowda)

Norbert W. Brattig, Klara Tenner-Racz, Simone Korten, Achim Hoerauf, Dietrich W. Büttner

Journal:

Parasitology Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2010

45

Strong expression of TGF-beta in human host tissues around subcutaneousDirofilaria repens

Norbert W. Brattig, Paul Racz, Achim Hoerauf, Dietrich W. Büttner

Journal:

Parasitology Research

Année:

2011

Langue:

english

Fichier:

PDF, 977 KB

english, 2011

46

Down-regulation of hypusine biosynthesis in plasmodium by inhibition ofS-adenosyl-methionine-decarboxylase

Robert Blavid, Peter Kusch, Joachim Hauber, Ute Eschweiler, Salem Ramadan Sarite, Sabine Specht, Susanne Deininger, Achim Hoerauf, Annette Kaiser

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1013 KB

english, 2010

47

The variant Arg110Gln of human IL-13 is associated with an immunologically hyper-reactive form of onchocerciasis (sowda)

Achim Hoerauf, Susanne Kruse, Norbert W. Brattig, Andrea Heinzmann, Bertram Mueller-Myhsok, Klaus A. Deichmann

Journal:

Microbes and Infection

Année:

2002

Langue:

english

Fichier:

PDF, 103 KB

english, 2002

48

Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?

Beate Henrichfreise, Andrea Schiefer, Tanja Schneider, Edith Nzukou, Christina Poellinger, Theo-Julian Hoffmann, Kelly L. Johnston, Katja Moelleken, Imke Wiedemann, Kenneth Pfarr, Achim Hoerauf, Hans

Journal:

Molecular Microbiology

Année:

2009

Langue:

english

Fichier:

PDF, 495 KB

english, 2009

49

Reliable and frequent detection of adult Wuchereria bancrofti in Ghanaian women by ultrasonography

Sabine Mand, Alex Debrah, Linda Batsa, Ohene Adjei, Achim Hoerauf

Journal:

Tropical Medicine & International Health

Année:

2004

Langue:

english

Fichier:

PDF, 80 KB

english, 2004

50

Macrofilaricidal effect of 4 weeks of treatment with doxycycline on Wuchereria bancrofti

Alexander Yaw Debrah, Sabine Mand, Yeboah Marfo-Debrekyei, Linda Batsa, Kenneth Pfarr, Marcelle Buttner, Ohene Adjei, Dietrich Buttner, Achim Hoerauf

Journal:

Tropical Medicine & International Health

Année:

2007

Langue:

english

Fichier:

PDF, 180 KB

english, 2007